Scientists have produced healthy offspring without fertilising an egg in a breakthrough that overturns two centuries of received wisdom.
Biologists at Bath university in the UK bred mice by injecting sperm into a non-viable type of embryo called a parthenogenote. This has dividing cells that are fundamentally different from eggs and more like other cells in the body.
Tony Perry, senior author of the study, said the research could in principle open the way to a “speculative and fanciful” scenario in which sperm are made to fertilise adult cells derived from skin or other tissues. It could even allow two men to become the biological parents of a baby, without female involvement.
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